Trypanosomiasis *Being a Paper read at a Meeting of the Bombay Medical and Physical Society.

a disease in the human being, which is characterised by certain symptoms of fever of long continuance, gradual and general deterioration in health, ansemia, a peculiar condition of the skin, and a profound affection of the nervous system?all of which are also associated with the detection in the blood and the cerebrospinal fluid of a peculiar parasite?the trypanosoma. The discovery of this parasite in human blood in such cases has given a great impetus to the investigation of the blood in diseases of certain tropical regions, and the most recent startling announcement is that of the presence of a trypanosoma in the cerebro-spinal fluid of cases of sleeping sickuess. A parasite of this description had, however, been observed in animals for some time, and the organism of surra has long been familiar to observers in India, but the discovery of such a parasite in the human being in so-called trypanosomiasis, in sleeping sickness (apparently the acute form of trypanosomiasis) and in forms of spleno-megaly diseases which are peculiar to Africa, is of more recent date, though the exact relationship of the parasite to each disease is